Development of bone substitute: poly(epsilon-caprolactone) scaffold functionalized by adhesive peptides in combination with soluble BMP-9
نویسندگان
چکیده
منابع مشابه
Mathematically and experimentally defined porous bone scaffold produced for bone substitute application
Objective (s): Artificial bone implants have been studied as a possible bone replacement for fractured and destroyed facial tissue; the techniques employed to determine the success of the dental implants. The stability, porosity and resistance of the bone implant which is subjected to varying forces and stresses within the surrounding bone is a subject of interest among the dentists. Materials ...
متن کاملFibrin Hydrogel Based Bone Substitute Tethered with BMP-2 and BMP-2/7 Heterodimers
Current clinically used delivery methods for bone morphogenetic proteins (BMPs) are collagen based and require large concentrations that can lead to dangerous side effects. Fibrin hydrogels can serve as osteoinductive bone substitute materials in non-load bearing bone defects in combination with BMPs. Two strategies to even further optimize such a fibrin based system include employing more pote...
متن کاملDevelopment of an antibacterial porous scaffold for bone defect treatment
Background & Aim: The use of bone scaffolds is one of the new and efficient techniques for repairing bone defects that provide a suitable platform for cell proliferation and growth to repair the target tissue. One of the most important causes of failure of transplants and surgical procedures is the invasion of bacteria at the site of the complication and the development of severe infection. The...
متن کاملDesigning of Human Cartilage Tissue, by Differentiation of Adipose-Derived Stem Cells With BMP-6 in Alginate Scaffold
Purpose: In the present study the effect of BMP-6 was investigated on chondrogenesis of adiposederived stem cells. Materials and Methods: Mesenchymal stem cells derived from subcutaneous adipose tissue were cultured on alginate scaffold to induce chondrogenesis in experimental group, with chondrogenic medium having BMP-6 growth factor for 3 weeks. In control group medium without BMP-6 was appli...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.00311